pharmpy.modeling.add_administration#

pharmpy.modeling.add_administration(td, arm, variable, amount, time_points, start_time=0.0)[source]#

Add observations to an arm in a trial design

Parameters:

  • td (TrialDesign) – TrialDesign to add to

  • arm (str) – Name of the arm

  • variable (str) – Name of the dose variable (e.g. AMT)

  • amount (float) – The dose amount

  • time_points (Sequence[float]) – List of the time points for the administration

  • start_time (float) – Set a start_time to offset the time_points. Default 0.0

Returns:

TrialDesign – An updated TrialDesign

Example

>>> from pharmpy.modeling import create_trial_design, add_arm, add_observations
>>> from pharmpy.modeling import add_administration
>>> td = create_trial_design()
>>> td = add_arm(td, name="Drug", size=100)
>>> td = add_observations(td, arm="Drug", variable="DV", time_points=[0.0, 1.0, 2.0, 4.0, 16.0])
>>> td = add_administration(td, arm="Drug", variable="AMT", amount=10.0, time_points=[0.0, 8.0])
>>> td
        ╭────── Observations ──────╮
  Drug  │ 0.0, 1.0, 2.0, 4.0, 16.0 │
        ╰─────────── DV ───────────╯
        ╭───── Administration ─────╮
        │ 0.0, 8.0                 │
        ╰─────── 10.0 Bolus ───────╯
        ├──────────────────────────┤
       0.0                       16.0
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