check_parameters_near_bounds#

pharmpy.modeling.check_parameters_near_bounds(model, values, zero_limit=0.001, significant_digits=2)[source]#

Check if any estimated parameter value is close to its bounds

Parameters:

  • model (Model) – Pharmpy model object

  • values (pd.Series) – Series of values with index a subset of parameter names.

  • zero_limit (float) – maximum distance to 0 bounds

  • significant_digits (int) – maximum distance to non-zero bounds in number of significant digits

Returns:

pd.Series – Logical Series with same index as values

Example

>>> from pharmpy.modeling import *
>>> from pharmpy.tools import load_example_modelfit_results
>>> model = load_example_model("pheno")
>>> results = load_example_modelfit_results("pheno")
>>> check_parameters_near_bounds(model, results.parameter_estimates)
POP_CL     False
POP_VC     False
COVAPGR    False
IIV_CL     False
IIV_VC     False
SIGMA      False
dtype: bool