calculate_se_from_prec#

pharmpy.modeling.calculate_se_from_prec(precision_matrix)[source]#

Calculate standard errors from a precision matrix

Parameters:: precision_matrix (pd.DataFrame) – Input precision matrix
Returns:: pd.Series – Standard errors

Examples

>>> from pharmpy.modeling import calculate_se_from_prec
>>> from pharmpy.tools import load_example_modelfit_results
>>> results = load_example_modelfit_results("pheno")
>>> prec = results.precision_matrix
>>> prec
               POP_CL        POP_VC       COVAPGR         IIV_CL        IIV_VC          SIGMA
POP_CL   2.993428e+07  22261.039122  16027.859538  203633.930854 -39113.269503 -817314.801755
POP_VC   2.226104e+04   2129.852212    260.115313    -373.896066  -2799.330946   -7697.921603
COVAPGR  1.602786e+04    260.115313    187.053488     177.987340   -205.261483   -2224.522815
IIV_CL   2.036339e+05   -373.896066    177.987340    7542.279597   2472.034556  -10209.416944
IIV_VC  -3.911327e+04  -2799.330946   -205.261483    2472.034556  22348.216559    9193.203130
SIGMA   -8.173148e+05  -7697.921603  -2224.522815  -10209.416944   9193.203130  249978.454601
>>> calculate_se_from_prec(prec)
POP_CL     0.000210
POP_VC     0.026895
COVAPGR    0.083756
IIV_CL     0.013416
IIV_VC     0.007476
SIGMA      0.002280
dtype: float64